Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.
Peripheral regulatory CD4+ T cells (Treg cells) prevent maladaptive inflammatory responses to innocuous foreign antigens.Treg cell dysfunction has been linked to many inflammatory diseases, including allergic airway inflammation.Glucocorticoids that are used to treat allergic airway inflammation and asthma are thought to work in part by promoting T